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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF4B
All Species:
27.27
Human Site:
S756
Identified Species:
40
UniProt:
Q2VIQ3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2VIQ3
NP_001092763.1
1234
140035
S756
N
E
I
E
V
M
V
S
T
E
E
A
K
R
H
Chimpanzee
Pan troglodytes
XP_518055
1227
139177
S749
N
E
I
E
V
M
V
S
T
E
E
A
K
R
H
Rhesus Macaque
Macaca mulatta
XP_001084213
1234
139742
S756
N
E
I
E
V
M
V
S
T
E
E
A
K
R
H
Dog
Lupus familis
XP_549061
1234
139874
S757
N
E
I
E
V
M
V
S
T
E
E
A
K
R
H
Cat
Felis silvestris
Mouse
Mus musculus
P33174
1231
139533
S757
N
E
I
E
V
M
V
S
T
E
E
A
K
R
H
Rat
Rattus norvegicus
Q7M6Z5
1394
158861
D846
S
E
L
E
Q
N
V
D
H
L
K
Y
Q
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90640
1225
138905
S762
N
E
V
E
V
L
V
S
T
E
E
A
R
R
H
Frog
Xenopus laevis
Q91784
1226
138905
S759
N
E
V
E
V
L
V
S
T
E
E
A
Q
R
H
Zebra Danio
Brachydanio rerio
Q58G59
1363
154819
L853
Q
D
L
L
Q
R
R
L
R
E
E
S
Q
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
P354
Q
P
I
K
N
E
D
P
Q
D
A
K
L
K
E
Honey Bee
Apis mellifera
XP_395595
1064
123475
K628
D
K
Q
D
Q
Q
I
K
N
L
T
N
E
M
Q
Nematode Worm
Caenorhab. elegans
P46873
699
78760
L269
L
G
N
V
I
S
A
L
V
D
G
K
S
K
H
Sea Urchin
Strong. purpuratus
P46872
699
78679
K269
Q
R
L
K
E
A
T
K
I
N
L
S
L
S
T
Poplar Tree
Populus trichocarpa
XP_002302432
1055
118553
Q615
K
K
E
E
N
Q
V
Q
L
L
K
Q
K
Q
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200901
1294
145204
A723
Y
E
M
H
K
L
M
A
L
N
Q
K
Q
K
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
M498
S
E
S
N
E
F
K
M
Q
L
E
R
L
A
F
Conservation
Percent
Protein Identity:
100
97.9
90.9
91
N.A.
83.6
26.4
N.A.
N.A.
71.3
66.6
25.1
N.A.
27.2
36.8
25.6
27.4
Protein Similarity:
100
98.8
94
94.7
N.A.
90.3
47.2
N.A.
N.A.
83.7
80.1
44.1
N.A.
41
55.8
38.5
38.4
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
N.A.
80
80
13.3
N.A.
6.6
0
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
53.3
N.A.
N.A.
100
100
46.6
N.A.
26.6
33.3
26.6
20
Percent
Protein Identity:
31.9
N.A.
N.A.
30.6
N.A.
26.6
Protein Similarity:
50
N.A.
N.A.
49.1
N.A.
44
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
40
N.A.
N.A.
53.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
7
7
0
0
7
44
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
7
0
0
7
7
0
13
0
0
0
0
0
% D
% Glu:
0
63
7
57
13
7
0
0
0
50
57
0
7
0
7
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
50
% H
% Ile:
0
0
38
0
7
0
7
0
7
0
0
0
0
0
0
% I
% Lys:
7
13
0
13
7
0
7
13
0
0
13
19
38
25
13
% K
% Leu:
7
0
19
7
0
19
0
13
13
25
7
0
19
0
7
% L
% Met:
0
0
7
0
0
32
7
7
0
0
0
0
0
7
0
% M
% Asn:
44
0
7
7
13
7
0
0
7
13
0
7
0
0
0
% N
% Pro:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
19
0
7
0
19
13
0
7
13
0
7
7
25
13
7
% Q
% Arg:
0
7
0
0
0
7
7
0
7
0
0
7
7
44
0
% R
% Ser:
13
0
7
0
0
7
0
44
0
0
0
13
7
7
0
% S
% Thr:
0
0
0
0
0
0
7
0
44
0
7
0
0
0
7
% T
% Val:
0
0
13
7
44
0
57
0
7
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _